Understanding Hydroxyeicosatetraenoic Acid (12-HETE) and Its Detection Using ELISA Kits
Hydroxyeicosatetraenoic acids (HETEs) are oxygenated derivatives of arachidonic acid, which play significant roles in various physiological and pathological processes. Among the different HETE isomers, 12-HETE is a major metabolite generated by the 12-lipoxygenase (12-LOX) enzyme, influencing inflammation, cancer progression, and vascular functions. Due to its critical role in disease mechanisms, precise quantification of 12-HETE is…